Rynex 0.025 Nasal Drops

Indications

Nasal congestion caused by acute or chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, epistaxis, and hay fever can all be treated with Oxymetazoline hydrochloride. In the case of otitis media, it is also utilized as a nasal decongestant.

Pharmacology

Oxymetazoline Hydrochloride is a sympathomimetic amine that is derived from imidazoline. It acts as a direct agonist on -adrenoceptors but not on -adrenoceptors. When applied topically to the nasal mucosa, it causes fast and long-acting vasoconstriction of the arterioles, which reduces blood flow and reduces mucosal edema. As a result, the airway's potency improves, and the nasal sinuses drain more effectively.

Dosage & Administration

Oxymetazoline nasal spray-

• Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
• Elderly: There is no need for dosage reduction in the elderly for nasal administration.
• Children below 6 years of age: It is not suitable for children below 6 years of age.

Oxymetazoline nasal drop-

• Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
• Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening

How to use the Nasal Spray-
 

Shake the bottle gently and remove the dust cover.

Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.

Gently blow the nose to clear the nostrils.

Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white collar of the nasal applicator firmly down once to release a spray.

Breathe out through your mouth.

Repeat the above steps in the same/another nostril for consecutive doses.

Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows
 

• Remove the dust cover.
• Gently pull off the nasal applicator.
• Wash the applicator and dust cover in warm water.
• Shake off the excess water and leave it to dry in a normal place. Avoid applying additional heat.
• Gently push the applicator back on the top of the bottle and re-fix the dust cover.

Interaction

Patients using MAO inhibitors or those who have just stopped taking them should not use Oxymetazoline Hydrochloride Nasal Preparation.

Grapefruit and grapefruit juice should not be consumed at the same time as Rupatadine.

Contraindications

Cardiovascular illness, hyperthyroidism, prostatic enlargement, angle closure glaucoma, and allergy to any of the components are all contraindications.

Side Effects

It might cause local irritation and dryness of the mouth and throat on occasion. Burning, stinging, sneezing, or an increase in nasal discharge may occur for a short time.

Pregnancy & Lactation

Although the safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and breastfeeding has not been proven, it is not believed to pose a risk during these times.

Precautions & Warnings

Keep your distance from the eyes. Without medical guidance, the spray should not be used for more than seven days. Nasal congestion may return or worsen if used often or for an extended period of time.

Storage Conditions

Keep below 30° C temperature in a dry place, and protect from light. Do not refrigerate or freeze. Keep out of the reach of children.